The Problem: Hemodialysis Access Issues

  • More than 600,000 individuals with End-Stage Renal Disease (ESRD) in the U.S. costing the
    healthcare system nearly $30 billion per year. 1
  • Hemodialysis (HD) is the most common treatment option for patients with ESRD.1
  • Most patients on HD rely on a functioning AV fistula or graft to provide permanent blood access. 2

There are several serious complications resulting from frequent, repeated cannulations with large bore (14 to 16 gauge) needles in the hemodialysis setting, including:

Bleeding – caused by venous needle and access site clot dislodgement.3

Pseudoaneurysms – results from hemodynamic loading and vessel wall degradation due to >300 cannulations per year.4

Thrombosis – partly due to disruption or cessation of blood flow resulting from prolonged compression applied to achieve post-dialysis hemostasis.5,6

1. USRDS 2013 Annual Data Report.
2. Fistula First Catheter Last Workgroup Coalition, September 2014.
3. Hurst J. (2010) Renal Business Today. 5(9): 18-22.
4. Katzman HE, et al. J Am Coll Surg. 2005, 201:223-30.
5. Ludlow V. (2010) CANNT J. 20(1):29-37.
6. Keuter X, et al. (2008) J Vasc Surg. 47(2):395-401.